Transient Receptor Potential

There is a real need to make clear to what "transient" refers in a transient receptor potential, and the advice of the wider community is solicited to fill this need. The corresponding acronym, TRP, is appended to at least three classes of ion channel, which mediate the response of a cell to external stimuli (electrical charge, substances, and forces) by increasing or decreasing its selective permeability to particular ions. The effect of this change is to modify the potential difference between inside and outside of cell. Hence "receptor," for sensitivity to the environment, and "potential" for this difference. Does the "transience" suggest fatigue effects? Or, are there any "invariant receptor potentials" that need compared?

 

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