Pre-replication Complex
A
pre-replication complex
is a
protein complex
that forms at the
origin of replication
during the initiation step of
DNA replication
. The following factors make up the complex:
A
helicase
, which unwinds the DNA ahead of the fork (
dnaA
).
A
primase
, which generates an
RNA
primer to be used in DNA replication (
dnaG
).
A
DNA holoenzyme
, which is actually a complex of enzymes that performs the actual replication.
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