polyclonal antibody

Polyclonal antibodies are antibodies that are derived from different cell lines. These antibodies are typically produced by immunization of a suitable mammal, such as a mouse or rabbit. An antigen is injected into the mammal. This induces the B-lymphocytes to produce IgG immunoglobulins specific for the antigen. This IgG is purified from the mammals serum. Several lines of B-lymphocytes produce these antibodies. These antibodies have specificity for different epitopes. By contrast, monoclonal antibodies are derived from a single cell line.

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