Paraneoplastic Phenomenon
A
paraneoplastic phenomenon
is a
disease
or
symptom
that is the consequence of the presence of
cancer
in the body, but is not due to the local presence of cancer cells. A large number of these phenomena are mediated by the
immune system
. Examples of paraneoplastic phenomena:
Lambert-Eaton myasthenic syndrome
(LEMS) in small-cell
lung cancer
Hypercalcemia
in
breast cancer
and
lung cancer
due to the production of
PTHrP
(Parathyroid hormone-related protein)
Granulocytosis
(increased
granulocytes
) due to the production of
G-CSF
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