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List Of Mad ScientistsThe following is a list of fictional mad scientists in cultural sources (literature, movies, comics, etc.). They are split into pre- and post-1945, as the images of mad scientists changed and proliferated in the years following the atomic bombings of Hiroshima and Nagasaki, and the increased role of scientists following World War II. For a list of real people who have inspired the "mad scientist" trope, see "Mad scientist: Real-life prototypes". Before 1945 Novels - Dr. Faust, figure of novels and plays (e.g. by Christopher Marlowe and J.W. von Goethe), based on a real figure from the 16th century.
- Dr. Frankenstein, creator of Frankenstein's monster, in the novel Frankenstein, or the Modern Prometheus by Mary Shelley (1818).
- Nathaniel Hawthorne, in his short story "The Birthmark" (1843), shows a scientist who, while perhaps not mad, is certainly overconfident, and whose meddling with nature brings about tragedy.
- Robert Louis Stevenson's The Strange Case of Dr. Jekyll and Mr. Hyde (1886) portrays the essentially humane experimenter driven to madness and suicide by the nature of his science.
- Jules Verne's Carpathian Castle (1892) has a mad scientist named "Orfanik".
- H. G. Wells' The Island of Dr. Moreau (1896) carried Frankensteinian experimentation a step further with its mad scientist Dr. Moreau, contrasting it with an idyllic 'natural' South Sea island setting. Several film versions were made (such as The Island of Lost Souls (1933)).
- Phor Tak, the discoverer of invisibility in Edgar Rice Burroughs' 1930 science-fiction novel, A Fighting Man of Mars.
Movies - The Cabinet of Dr. Caligari (1919) is a silent film featuring the mad hypnotic doctor and his sleepwalking assistant.
- Dr. Mabuse, most famous from the films made about him by Fritz Lang
- Dr. Herbert West, a Frankenstein-like doctor obsessed with bringing the dead back to life, in H. P. Lovecraft's novella "Herbert West, Reanimator" (1922).
- C.A. Rotwang in Fritz Lang's Metropolis (1927).
- Dr. Frankenstein in several movie versions.
- Dr. Jack Griffin, in the film The Invisible Man (1933). Dr. Griffin makes a discovery on how to become invisible but in the process is sent into murderous insanity.
- Dr. Janos Rukh, in the film The Invisible Ray (1936). Dr. Rukh discovers a radioactive ray that cures blindness but causes him to develop a murderous paranoid rage against other scientists, whom he accuses of stealing his discovery.
- Dr. Throkel, in the film Dr. Cyclops (1940). Dr. Throkel shrinks opponents of his unorthodox experimentation with radium.
After 1945 Novels - Dr. Jacob (Jake) Jeremiah Burroughs, Colonel, A.U.S. from Robert A. Heinlein's The Number of the Beast (1980) (Although Heinlein used the term "Mad Scientist" to describe him, he doesn't exhibit many of the characteristics.)
- The Mad Scientists' Club: a book series that portrayed seven oddball teens who are actually good scientists and brave adventurers rather than wacky science freaks
- Dr. Lazlo Zand, from the Robotech novels by Jack Mckinney
- Vergil Ulam, in the Greg Bear novel Blood Music
- Dr. Chaotica from the "Bride of Chaotica" episode in
- Davros and The Rani, from Doctor Who
- Degra, from
- Dr. Clayton Forrester, from Mystery Science Theater 3000, ironically named after the hero scientist in the 1953 film The War of the Worlds
- Xavier Mace, a recurring adversary in a 1990s series of Tom Swift, Jr. books
- Dr. Hugo Grief from the Alex Rider book Point Blanc
- various parodies in Terry Pratchett stories, including Igor the manservant
Movies - Dr. Victor Frankenstein (in the film versions, at least)
- Dr. Edward Morbius, in the film Forbidden Planet (1956)
- Sebastian Caine, in the film Hollow Man (2000)
- Dr. Otto Frank, in the film Monstrosity (1964)
- Dr. Durand Durand, in the film Barbarella (1968)
- Dr. Charles Girard, in the film Terror Is a Man (1959)
- Dr. Emmett Brown in the Back to the Future film trilogy
- Dr. Richard Benjamin Vannacutt from the film House on Haunted Hill (1999)
- Krank, and the doctor who made him, in the film The City of Lost Children (1995)
- The protagonists of Ghostbusters
- Ernst Stavro Blofeld from James Bond, head of SPECTRE.
- Dr. Seth Brundle in David Cronenberg's remake of The Fly
- David Banner, in Hulk
- Dr. Hannibal Lecter in The Silence of the Lambs (rather psychopatic genius)
- Dr. Hans Reinhardt, in the film The Black Hole (1979)
- Michael Sharrington, in the film Graveyard of Horror (1971)
- Dr. Evil, from the Austin Powers film series
- Dr. Tolian Soran from the Star Trek film
- Dr. Susan Harris, in the film Invasion of the Bee Girls (1973)
- Dr. Paul Holliston, in the film Embryo (1976)
- Dr. Kurt Leopold, in the film Zaat (1972)
- Dr. Emilio Lizardo, in the film The Adventures of Buckaroo Banzai Across the 8th Dimension (1984)
- Dr. Lorca, in the film Mad Doctor of Blood Island (1968)
- Dr. Arliss Loveless, in the film Wild Wild West (1999)
- Dr. Arik Soong from
- Dr. Noonien Soong from
- Dr. Carl Stoner, in the film Ssssss (1973)
- The title character, born Mr. Merkwrdigliebe, in the film Dr. Strangelove (1964)
- Dr. Sy N. Tist, from the Mad Scientist series
- Dr. Eric Vornoff (Bela Lugosi) in ''Bride of the Monster'
- E. Nigma, aka The Riddler, in the 1995 movie Batman Forever
- Professor Wendland, in the film Superargo (1968)
- Dr. Herbert West, in the film Re-Animator (1985)
- Dr. Totenkopf, in the film Sky Captain and the World of Tomorrow (2004)
- Professor Nolter, in the film The Mutations (1973)
- Buddy Love, from the film The Nutty Professor (PArt 1: 1996, Part 2: 2000)
- Sir August DeWynter, in the film The Avengers (1998)
- Elizabeth, from Wicked Science
TV series Cartoon/anime - The Professor, from the cartoon series Felix the Cat
- Professor Squarkencluck, from the cartoon Dangermouse
- Dr. Blight, a female mad scientist specialising in genetic engineering and air pollution, from Captain Planet and the Planeteers
- Dr. Nora Wakeman, from the TV series My Life as a Teenage Robot
- Prof. John Frink from The Simpsons
- Professor Hubert Farnsworth from the cartoon series Futurama
- Dexter and Mandark, of Dexter's Laboratory
- Simon Bar Sinister, from the Underdog cartoon (1964)
- Dr. Jumba Jookiba, from the Lilo & Stitch cartoons and movies
- Dr. Putrid T. Gangreen from the cartoon series Attack of the Killer Tomatoes (1994)
- Dr. Mephesto from South Park
- Hugo A Go Go, from the cartoon series Batfink
- rotcoD daM, from the cartoon series Sinbad the Sailor
- Mojo Jojo and Professor Utonium from The Powerpuff Girls
- The Brain, from Pinky and the Brain
- Dr. X, from Action Man
- Mr. Paulson, from Teamo Supremo cartoon series
- Dr. Zin, from the Jonny Quest cartoon series
- Baxter Stockman and occasionally Donatello from the Teenage Mutant Ninja Turtles
- Newton Gimmick in "The Adventures of Teddy Ruxpin"
- Carl Foutley (aspiring), on As Told By Ginger
- Dr. Weird from Aqua Teen Hunger Force
- Dr. Umataro Tenma in the manga/anime Astro Boy
- Dr. Saruta from the Tezuka manga Phoenix: Future
- "Icchan" Miehara from Angelic Layer
- Dr. Hell from anime Go Nagai's Mazinger Z
- Dr. Agasa from manga/anime Detective Conan
- Washu Hakubi in the anime series Tenchi Muyo!
- Dr. Desty Nova from the anime/manga series Battle Angel Alita, who used Nanotechnology to try to overcome the human Karma.
- Professor Samuel Oak from the Pokmon franchise. A leading figure in Pokmon research and specialist in Pokmon behavioural science.
Comics - Lex Luthor, arch-enemy of Superman
- Sivana from DC Comics
- Mr. Fantastic and Doctor Doom from the Fantastic Four
- Both Doctor Octopus and Kurt Connors (The Lizard) in Spider-Man, who went mad and became evil after an experiment mutated or altered them
- Egghead and Dr. Henry Pym from Marvel comics
- Green Goblin(Norman Osborn), who became insane after a laboratory accident
- Dr. August Hopper a.k.a. The Locust, from the X-Men comics
- Dr. Light, enemy of the Teen Titans
- Baron Karza from the Micronauts comic book
- Prof. Septimus in Blake and Mortimer's "The Yellow Mark"
- Professor Cuthbert Calculus (Professeur Tryphon Tournesol) from The Adventures of Tintin.
- Professor Miloch Georgevitch in Blake and Mortimer's "The Diabolical Trap"
- Champignac and Zorglub in Spirou (occasionally Fantasio)
- Baron Klaus von Wulfenbach, Agatha Heterodyne (one of the rare females), and other sparks, from Phil Foglio's Girl Genius comics
- Helen Narbon, Helen Beta Narbon, Wolf Madblood, and others in the webcomic Narbonic
- Casey and Andy from the webcomic Casey and Andy
Video games - Dr. Albert W. Wily, from the video game series Mega Man
- Dr. Hans Ubermann, from the Indiana Jones and the Fate of Atlantis adventure game (1992)
- Dr. Fred Edison, from adventure games Maniac Mansion and Day of the Tentacle
- Dr. Eggman, aka Dr. Ivo Robotnik, from the Sonic the Hedgehog series
- Dr. Gerald Robotnik, Dr. Eggman's grandfather
- Dr. Brain, from the educative video games Island of Dr. Brain, Castle of Dr. Brain and The Lost Mind of Dr. Brain
- Dr. Malcolm Betrger, from Doom 3
- Dr. Bomb, from platform game Bravoman
- Dr. Ironstein, from the Flight of the Amazon Queen adventure game (1995)
Mad scientists
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