levofloxacin

bgcolor="#ffffff" align="center" colspan="2" \| Levofloxacin
align="center" colspan="2" \| (-)-(S)-9-fluoro-2,3-dihydro-3-methyl- 10-(4-methyl-1-piperazinyl)-7-oxo- 7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
CAS number 100986-85-4	ATC code J01MA12, S01AX19
bgcolor="#eeeeee" \| Chemical formula	bgcolor="#ddeeff" \| CHFNO
bgcolor="#eeeeee" \| Molecular weight	bgcolor="#ddeeff" \| 361.371
bgcolor="#eeeeee" \| Bioavailability	bgcolor="#ddeeff" \| ?
bgcolor="#eeeeee" \| Metabolism	bgcolor="#ddeeff" \| ?
bgcolor="#eeeeee" \| Elimination half-life	bgcolor="#ddeeff" \| ?
bgcolor="#eeeeee" \| Excretion	bgcolor="#ddeeff" \| ?
bgcolor="#eeeeee" \| Pregnancy category	bgcolor="#ddeeff" \| ?
bgcolor="#eeeeee" \| Legal status	bgcolor="#ddeeff" \| ?
bgcolor="#eeeeee" \| Routes of administration	bgcolor="#ddeeff" \| ?

Levofloxacin is relatively new fluoroquinolone antibiotic, marketed by Ortho-McNeil under the brand name Levaquin. Chemically, Levofloxacin is the S-enantiomer (L-isomer) of ofloxacin. Levofloxacin is effective against a number of gram-positive and gram-negative bacteria. Because of its broad spectrum of action, levofloxacin is frequently prescribed in hospitals for pulmonary infections before the specific causal organisim is known. Once the causal organisim is known, levofloxacin is discontinued and the patient is given a narrow-spectrum antibiotic.

Gram-positive bacteria

Enterococcus faecalis (many strains are only moderately susceptible)
Staphylococcus aureus (methicillin-susceptible strains)
Staphylococcus epidermidis (methicillin-susceptible strains)
Staphylococcus saprophyticus
Streptococcus pneumoniae (including penicillin-resistant strains*)
Streptococcus pyogenes

Gram-negative bacteria

Other

Some information extracted from Levaquin Prescribing information.

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