Klippel Feil Syndrome

Klippel Feil Syndrome (KFS) is a rare disorder characterized by the congenital fusion of any 2 of the 7 cervical vertebrae. It is caused by a failure in the normal segmentation of the cervical vertebrae during the early weeks of fetal development. The most common signs of the disorder are short neck, low hairline at the back of the head, and restricted mobility of the upper spine. Associated abnormalities may include scoliosis, spina bifida, anomalies of the kidneys and the ribs, cleft palate, respiratory problems, and heart defects. KFS may also be associated with abnormalities of the head and face, skeleton, sex organs, muscles, brain and spinal cord, arms, legs, and fingers. Treatment for KFS is symptomatic and may include surgery to relieve cervical or craniocervical instability and constriction of the spinal cord, and to correct scoliosis. The prognosis for most individuals with KFS is good if the disorder is treated early and appropriately. Activities that can injure the neck should be avoided. The 18th Dynasty Egyptian pharoah Tutankhamun is believed to have suffered from Klippel Feil syndrome.

 

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