Ketone Halogenation

In organic chemistry ketone halogenation is a special type of halogenation. The position alpha (next) to the carbonyl group in a ketone is easily halogenated, due to the ability to form a enolate in basic or acidic solution. An example is the bromination of acetone in basic solution: CH3-CO-CH3 + OH- → CH3-CO-CH2- + H2O CH3-CO-CH2- + Br2 → CH3-CO-CH2Br + Br- This reaction has two steps, but is not a chain reaction. Multiple bromination can occur giving CH3-CO-CHBr2 etc.

 

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