Ketanserin

Ketanserin
Chemical name-
Chemical formulaC22H22FN3O3
Molecular mass395.43 g/mol
CAS number74050-98-9
SMILESO=C(C4=CC=C(F)C=C4)C(CC3)CCN3
CCN(C2=O)C(NC1=C2C=CC=C1)=O
chemical structure of ketanserin
Ketanserin is a serotonin receptor antagonist. It has the highest affinity for the serotonin 5-HT2A receptor, but also binds less potently to the 5-HT2C, 5-HT2B, 5-HT1D, alpha-adrenergic, and dopamine receptors. With tritium radioactively labeled ketanserin is used as a radioligand for the serotonin 5-HT2A receptor, e.g. in receptor binding assays.

 

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