Harmala

Harmala is a blanket term for the group of naturally occurring beta-carbolines including harmine, harmaline, and others. The harmala alkaloids are tryptamines and monoamine oxidase inhibitors. They also act as serotonin antagonists and CNS stimulants. Harmala is found most commonly in the seeds of Peganum harmala, where it occurs in concentrations of up to 3%, and also Banisteriopsis caapi, where it occurs in lower concentrations. In Caapi, it is used in combination with a DMT containing admixture to form a South American Entheogen known as Ayahuasca.

Chemical Forms

Harmine: C13H12N2O
  • 7-Methoxy-1-methyl-9H-pyrido3,4-bindole
Harmaline: C13H14N2O
  • 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido3,4-bindole
Tetrahydroharmine: C13H16N2O4P
  • 7-Methoxy-1,2,3,4-Tetrahydro-Harmine

 

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