Glyceraldehyde 3-Phosphate

Glyceraldehyde 3-phosphate (G3P) is an intermediate in both glycolysis and gluconeogenesis. G3P is formed from the following three reversible reactions:
  • Fructose-1,6-bisphosphate, catalyzed by aldolase
  • Dihydroxyacetone phosphate (DHAP), catalyzed by triose phosphate isomerase (TIM)
  • 1,3-bisphosphoglycerate, catalyzed by glyceraldehyde 3-phosphate dehydrogenase
This intermediate is also of some importance since this is how glycerol (as DHAP) enters the glycolytic and gluconeogenesis pathways.

 

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