Fenfluramine
bgcolor="#ffffff" align="center" colspan="2" |
align="center" colspan="2" |
IUPAC
name:
N-ethyl-1-
3-(trifluoromethyl)phenyl
-propan-2-amine
CAS number
404-82-0
bgcolor="#eeeeee" |
Chemical formula
bgcolor="#ddeeff" |
C
12
H
16
F
3
N
bgcolor="#eeeeee" |
Molecular weight
bgcolor="#ddeeff" | 267.7
bgcolor="#eeeeee" |
Bioavailability
bgcolor="#ddeeff" | ?
bgcolor="#eeeeee" | Metabolism
bgcolor="#ddeeff" | hepatic
bgcolor="#eeeeee" |
Elimination half-life
bgcolor="#ddeeff" | ?
bgcolor="#eeeeee" |
Excretion
bgcolor="#ddeeff" | ?
bgcolor="#eeeeee" |
Pregnancy category
bgcolor="#ddeeff" | ? (
United States
)
? (
Australia
)
bgcolor="#eeeeee" |
Legal status
bgcolor="#ddeeff" | ?
bgcolor="#eeeeee" | Route of administration
bgcolor="#ddeeff" | Oral
b>Indicated for:
obesity
Fenfluramine
is a drug that was part of the
Fen-Phen
anti-
obesity
(the other drug being
phentermine
). Also known as
Pondimin
, fenfluramine was introduced on the U.S. market in 1973. It is designed to increase the level of the
neurotransmitter
serotonin
. This depresses the
central nervous system
, regulating mood and appetite. The end result is a feeling of fullness and loss of appetite. The drug was withdrawn from the U.S. market in 1997 after reports of
heart valve disease
and
pulmonary hypertension
.
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