fecal elastase

Fecal elastase refers to the testing of the concentration of the pancreatic elastase-1 enzyme found in fecal matter with an enzyme-linked immunosorbent assay (ELISA). Results of this test can give a good indication of exocrine pancreatic status and is less invasive and expensive that the current gold standard, secretin-cholecystokinin test.¹ Levels of fecal elastase lower than 200 μg / g of stool indicate an exocrine insufficiency. Correlations between low levels and chronic pancreatitis² and cancer³ have been reported.

References

Molinari, I., et al., Fecal chymotrypsin and elastase-1 determination on one single stool collected at random: diagnostic value for exocrine pancreatic status. Clin Biochem, 2004. 37(9): p. 758-763. PMID 15329313
Fecal Elastase 1 ELISA For Exocrine Pancreatic Insufficiency: Comparison With ERCP-Morphology And Fecal Fat Excretion http://www.uniklinikum-giessen.de/med3/poster/publ_pdf/118.pdf
Role of Fecal Elastase 1 in Pancreatic Cancer: A Pilot Study http://www.joplink.net/prev/200409/59.html

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