Electrophilic Halogenation

In organic chemistry electrophilic halogenation is a type of halogenation. This chemical reaction is typical of aromatic compounds. This type of halogenation is a very useful method for adding substituents to an aromatic system. An example is the chlorination of benzene: Overall: C6H6 + Cl2 → C6H5Cl + HCl A few types of aromatic compounds, such as phenol, will react without a catalyst, but for typical benzene derivatives with less reactive substrates, a Lewis acid catalyst is required. Typical Lewis acid catalysts include AlCl3, FeCl3, FeBr3, and ZnCl2. These work by forming a highly electrophilic complex which attacks the benzene ring.

 

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