Casp
CASP
, which stands for
Critical Assessment of Techniques for Protein Structure Prediction
, is a contest for
protein structure prediction
taking place every two years. The goal of CASP is to provide research groups with an opportunity to assess the quality of their methods for
protein structure prediction
from the
primary structure
of the protein. Protein structures that have been recently resolved, but not yet published, are used as targets for the evaluation. If the given sequence is close to a proteins sequence with known structure (using sequence alignment methods such as
BLAST
or
FASTA
),
comparative protein modelling
is used to predict the
tertiary structure
. Otherwise, other methods such as
protein threading
or
de novo
protein structure prediction
are applied. The results of CASP are published
http://www3.interscience.wiley.com/cgi-bin/jissue/106558999
and are divided into several prediction categories:
secondary structure prediction
homology modelling
fold recognition
(also called protein threading)
contact prediction
de novo
structure prediction
function prediction
External links
CASP experiments home page
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