| width="20%"|Tenure | width="40%"|Incumbent | width="20%"|Notes |
| small>15 March 1623 to 13 April 1624 | Bishop William Bishop, Vicar Apostolic of England | Died in office |
| small>29 November 1624 to 1632 | Bishop Richard Smith, Vicar Apostolic of England | Resigned |
| small>24 August 1685 to 30 January 1688 | Bishop John Leyburn, Vicar Apostolic of England | Becoming Vicar Appostolic of London |
| small>30 January 1688 to 20 June 1702 | Bishop John Leyburn, Vicar Apostolic of the London District | Died in office |
| small>14 March 1703 to 12 March 1734 | Bishop Bonaventure Giffard, Vicar Apostolic of the London District | Died in office |
| small>12 March 1734 to 22 December 1758 | Bishop Benjamin Petre, OSB, Vicar Apostolic of the London District | Died in office |
| small>22 September 1758 to 12 January 1781 | Bishop Richard Challoner, Vicar Apostolic of the London District | Died in office |
| small>12 January 1781 to 26 January 1790 | Bishop James Robert Talbot, Vicar Apostolic of the London District | Died in office |
| small>10 September 1790 to 8 May 1812 | Bishop John Douglass, Vicar Apostolic of the London District | Died in office |
| small>8 May 1812 to 26 November 1827 | Bishop William Poynter, Vicar Apostolic of the London District | Died in office |
| small>26 November 1827 to 11 July 1836 | Bishop James Yorke Bramston, Vicar Apostolic of the London District | Died in office |
| small>11 July 1836 to 12 August 1847 | Bishop Thomas Griffiths, Vicar Apostolic of the London District | Died in office |
| small>17 July 1848 to 18 February 1849 | Bishop Thomas Walsh, Vicar Apostolic of the London District | Died in office |
| small>18 February 1849 to 29 September 1850 | Bishop Nicholas Patrick Stephen Wiseman, Vicar Apostolic of the London District | Nicols Patricio Esteban; becoming Archbishop |
| small>29 September 1850 to 30 September 1850 | Nicholas Patrick Stephen Wiseman, Archbishop of Westminster | Hitherto Vicar Apostolic; elevated to Cardinal |
| small>30 September 1850 to 15 February 1865 | Nicholas Patrick Stephen Cardinal Wiseman, Archbishop of Westminster | Died in office |
| small>30 April 1865 to 15 March 1875 | Henry Edward Manning, Archbishop of Westminster | Elevated to Cardinal |
| small>15 March 1875 to 14 January 1892 | Henry Edward Cardinal Manning, Archbishop of Westminster | Priest of Westminster; Ordained 8 June 1875; died in office |
| small>8 April 1892 to 16 January 1893 | Herbert Vaughan, Archbishop of Westminster | Bishop of Salford; died in office |
| small>16 January 1893 to 19 June 1903 | Herbert Cardinal Vaughan, Archbishop of Westminster | Died in office |
| small>11 September 1903 to 27 November 1911 | Francis Alphonsus Bourne, Archbishop of Westminster | Coadjutor Bishop of Southwark; elevated to Cardinal |
| small>27 November 1911 to 31 December 1934 | Francis Alphonsus Cardinal Bourne, Archbishop of Westminster | Died in office |
| small>1 April 1935 to 13 December 1937 | Arthur Hinsley, Archbishop of Westminster | Priest of Westminster; elevated to Cardinal |
| small>13 December 1937 to 17 March 1943 | Arthur Cardinal Hinsley, Archbishop of Westminster | Died in office |
| small>18 December 1943 to 18 February 1946 | Bernard William Griffin, Archbishop of Westminster | Auxiliary Bishop of Birmingham; elevated to Cardinal |
| small>18 February 1946 to 19 August 1956 | Bernard William Cardinal Griffin, Archbishop of Westminster | Died in office |
| small>3 December 1956 to 15 December 1958 | William Godfrey, Archbishop of Westminster | Archbishop of Liverpool; elevated to Cardinal |
| small>15 December 1958 to 22 January 1963 | William Cardinal Godfrey, Archbishop of Westminster | Died in office |
| small>2 September 1963 to 22 February 1965 | John Carmel Heenan, Archbishop of Westminster | Archbishop of Liverpool; elevated to Cardinal |
| small>22 February 1965 to 7 November 1975 | John Carmel Cardinal Heenan, Archbishop of Westminster | Died in office |
| small>9 February 1976 to 24 May 1976 | George Basil Hume, OSB, Archbishop of Westminster | Priest of the Order of Saint Benedict; elevated to Cardinal |
| small>24 May 1976 to 17 June 1999 | George Basil Cardinal Hume, OSB, Archbishop of Westminster | Died in office |
| small>15 February 2000 to 21 February 2001 | Cormac Murphy-O'Connor, Metropolitan Archbishop of Westminster | Bishop of Arundel and Brighton; elevated to Cardinal |
| small>21 February 2001 to present | Cormac Cardinal Murphy-O'Connor, Metropolitan Archbishop of Westminster | |