Angela Vincent
Angela Vincent
is a professor at
Somerville College
of
Oxford University
. She is the head of a research group, which is located in the Institute of Molecular Sciences and working on a wide range of
biological
disciplines encompassing
molecular biology
,
biochemistry
, cellular
immunology
and intracellular
neurophysiology
. The group's research is focused on autoimmune and
genetic disorders
of the neuromuscular junction and peripheral motor nerves. The principal autoimmune diseases studied are
myasthenia gravis
, the
Lambert-Eaton myasthenic syndrome
and acquired
neuromyotonia
. Her contributions are mainly on the roles of antibodies directed against
ion channel
at the
nerve
-
muscle
junction in the pathogenesis of above mentioned diseases. She has demonstrated that transfer of these
antibodies
across the
placenta
from the mother to the unborn baby in the
uterus
can cause developmental abnormalities. She has also worked on the principal gene
mutations
causing nerve-muscle disorders. Vincent, Angela
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