Sigma Factor
Sigma factor
(
σ factor
) is an
initiation
factor
that binds to
RNA polymerase
and promotes attachment to
promoter
sites on
DNA
.
Structure
Sigma factor has four main regions: N----------C
1 2 3 4
Region 1 regulates interaction with DNA.
Region 2 binds
RNAP
and binds to the -10
promoter
site.
Region 4 binds to the -35 promoter site.
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