| width="18%"|Tenure | width="35%"|Incumbent | width="10%"|Affiliation | width="20%"|Notes |
| small>1 October 1961 to 13 May 1965 | John Ngu Foncha, Prime Minister | KNDP | |
| small>13 May 1965 to 1966 | Augustine Ngom Jua, Prime Minister | UNC | |
| small>1966 to 11 January 1968 | Augustine Ngom Jua, Prime Minister | KNDP | |
| small>11 January 1968 to 2 June 1972 | Salomon Tandeng Muna, Prime Minister | UNC | |
| olspan="4"|Cameroun United Republic |
| small>2 June 1972 to 30 June 1975 | | | |
| small>30 June 1975 to 6 November 1982 | Paul Biya, Prime Minister | UNC | |
| small>6 November 1982 to 22 August 1983 | Bello Bouba Maigari, Prime Minister | UNC | |
| small>22 August 1983 to 25 January 1984 | Luc Ayang, Prime Minister | UNC | |
| olspan="4"|Cameroun Republic |
| small>25 January 1984 to 26 April 1991 | | | |
| small>26 April 1991 to 9 April 1992 | Sadou Hayatou, Prime Minister | RDPC | |
| small>9 April 1992 to 19 September 1996 | Simon Achidi Achu, Prime Minister | RDPC | |
| small>19 September 1996 to present | Peter Mafany Musonge, Prime Minister | RDPC | |