Churg-strauss Syndrome
Churg-Strauss syndrome
(also known as
allergic granulomatosis
) is a form of
vasculitis
due to
autoimmunity
, leading to
necrosis
. It involves mainly the
arteries
, the
lungs
(it begins as a severe type of
asthma
), and nerves. Churg-Strauss syndrome is classified both as a type of polyarteritis nodosa and, more broadly, as a diffuse
connective tissue
disease. Diagnostic markers include
eosinophil granulocytes
and
granulomas
in affected tissue and
cANCA
antibodies against
neutrophil granulocytes
. Differentiation from
Wegener's granulomatosis
can be difficult.
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