5-Alpha Reductase
5-alpha reductase
is an enzyme (
EC
1.3.99.5
) that converts
testosterone
, the male
sex hormone
, into
dihydrotestosterone
. There are two
isoenzymes
, steroid 5-alpha reductase 1 and 2 (SRD5A1 and SRD5A2). The second isoenzyme is deficient in
5-alpha-reductase deficiency
, which leads to a form of
intersexualism
.
Genetics
SRD5A1 is located on
chromosome
5p15, while SRD5A2 is located on 2p23.
Pharmacology
Finasteride
inhibits the function of only one of the isoenzymes (type 1), while
dutasteride
inhibits both forms. These drugs are used in
benign prostatic hyperplasia
,
prostate cancer
and
baldness
(finasteride).
External
(SRD5A1) and (SRD5A2)
<< Previous
Word Browser
Next >>
nils waltersen aasen
davis and elkins college
list of state leaders in 995
svatopluk
list of state leaders in 994
yahud
liberal government 1859 1866
j. h. hexter
the visby lenses
deputy secretary of commerce
finasteride
belem (ship)
patrick f. mcmanus
bedstone
mersey tunnels police
gina waggott
mersey tunnels
grail community
major league soccer 2000 season
maserati quattroporte
maserati coupe
guca
weaver rail mount
explorations (tv)
greatest hits (the cars)
analytic hierarchy process
thumb wars
richard gale
kamaloka
greater london linux users group
digby
entropy ry.
sadi moma
canada france hawaii telescope
stroud green
sam williams
tom knight
tupolev tu 125
horace pippin
charles enderlin
.dd
conservative government 1866 1868
bernard dillon
kamarupa
Copyright 2005-2009 OnPedia.com. All Rights Reserved