449

• August 3 - The Second Council of Ephesus opens, chaired by Dioscorus, Patriarch of Alexandria. Flavian, Patriarch of Constantinople, and Domnus II, Patriarch of Antioch, are deposed on August 8.
• October, a Roman synod repudiates all the decisions of the Second Council of Ephesus.
• Anatolius becomes Patriarch of Constantinople
• Maximus II becomes Patriarch of Antioch.
• Vortigern forms an alliance with Hengest and Horsa, by tradition chieftains of the Jutes, who led the Anglo-Saxon invasion of Britain. (traditional date)

• Kavadh I of Persia

• August 11 - Flavian of Constantinople
• Hilary of Arles

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