1516

align="center" colspan=2 | Years:
1513 1514 1515 - 1516 - 1517 1518 1519

align="center" colspan=2 | Decades:
1480s 1490s 1500s - 1510s - 1520s 1530s 1540s

align="center" | Centuries:
15th century - 16th century - 17th century

Events

March - With the death of Ferdinand II of Aragon, his grandson Charles of Ghent becomes King of Spain as Carlos I.
July - Selim I of the Ottoman Empire declares war on the Mameluks and invades Syria.
August 13 - Treaty of Noyon - Peace between France and Spain. Francis recognizes Charles's claim to Naples, and Charles recognizes Francis's claim to Milan.
August 24 - Battle of Merj-Dabik. The Ottomans defeat the Mameluks, who abandon Syria.
October 28 - Battle of Yaunis Khan. Turkish forces under the Grand Vizier Sinan Pasha defeat the Mameluks near Gaza.
December 4 - Treaty of Brussels - Peace between France and the Empire.
Pedro de Solis discovers the La Plata River.

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