| Noun | 1. | vacuum - the absence of matter | |
| 2. | vacuum - an empty area or space; "the huge desert voids"; "the emptiness of outer space"; "without their support he'll be ruling in a vacuum"space - an empty area (usually bounded in some way between things); "the architect left space in front of the building"; "they stopped at an open space in the jungle"; "the space between his teeth" | |
| 3. | vacuum - a region empty of matterregion, part - the extended spatial location of something; "the farming regions of France"; "religions in all parts of the world"; "regions of outer space" | |
| 4. | vacuum - an electrical home appliance that cleans by suctionHoover - a kind of vacuum cleaner | |
| Verb | 1. | vacuum - clean with a vacuum cleaner; "vacuum the carpets"clean, make clean - make clean by removing dirt, filth, or unwanted substances from; "Clean the stove!"; "The dentist cleaned my teeth" | |