tiredness - temporary loss of strength and energy resulting from hard physical or mental work; "he was hospitalized for extreme fatigue"; "growing fatigue was apparent from the decline in the execution of their athletic skills"; "weariness overcame her after twelve hours and she fell asleep"asthenopia, eyestrain - a tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem jet lag - fatigue and sleep disturbance resulting from disruption of the body's normal circadian rhythm as a result of jet travel grogginess - a groggy state resulting from weariness |