| Noun | 1. | Santiago - city in the northern Dominican Republiccity, metropolis, urban center - a large and densely populated urban area; may include several independent administrative districts; "Ancient Troy was a great city" Dominican Republic - a republic in the West Indies; located on the eastern two-thirds of the island of Hispaniola | |
| 2. | Santiago - port city in southeastern Chile; industrial centercity, metropolis, urban center - a large and densely populated urban area; may include several independent administrative districts; "Ancient Troy was a great city" port - a place (seaport or airport) where people and merchandise can enter or leave a country Cuba, Republic of Cuba - a communist state in the Caribbean on the island of Cuba; involved in state-sponsored terrorism | |
| 3. | Santiago - the capital and largest city of Chile; located in central Chile; one of the largest cities in South AmericaChile, Republic of Chile - a republic in southern South America on the western slopes of the Andes on the south Pacific coast | |
| 4. | Santiago - a naval battle in the Spanish-American War (1898); the United States fleet bottled up the Spanish ships in the harbor of Santiago de Cuba and destroyed them when they tried to escapeCuba - the largest island in the West Indies | |