desolation, devastation - the state of being decayed or destroyed

demolition, wipeout, destruction - an event (or the result of an event) that completely destroys something

devastation, desolation - an event that results in total destruction

shipwreck - an irretrievable loss; "that was the shipwreck of their romance"

failure - an event that does not accomplish its intended purpose; "the surprise party was a complete failure"

finish - the downfall of someone (as of persons on one side of a conflict); "booze will be the finish of him"; "it was a fight to the finish"

destruction, devastation - termination by an act of destruction