disorder, upset - condition in which there is a disturbance of normal functioning; "the doctor prescribed some medicine for the disorder"; "everyone gets stomach upsets from time to time"

brain disease, brain disorder, encephalopathy - any disorder or disease of the brain

ataxia, ataxy, dyssynergia, motor ataxia - inability to coordinate voluntary muscle movements; unsteady movements and staggering gait

atopognosia, atopognosis - absence or loss of topognosia; inability to locate correctly a point of touch

dyskinesia - abnormality in performing voluntary muscle movements

chorea - any of several degenerative nervous disorders characterized by spasmodic movements of the body and limbs

flaccid paralysis - weakness or loss of muscle tone resulting from injury or disease of the nerves innervating the muscles

ALS, amyotrophic lateral sclerosis, Lou Gehrig's disease - thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs

athetosis - a continuous succession of slow writing involuntary movements of the hands and feet and other body parts

kuru - a progressive disease of the central nervous system marked by increasing lack of coordination and advancing to paralysis and death within a year of the appearance of symptoms; thought to have been transmitted by cannibalistic consumption of diseased brain tissue since the disease virtually disappeared when cannibalism was abandoned

nerve compression - harmful pressure on a nerve (especially in nerves that pass over rigid prominences); causes nerve damage and muscle weakness