asperse, besmirch, calumniate, defame, slander, smirch, denigrate, sully, smear - charge falsely or with malicious intent; attack the good name and reputation of someone; "The journalists have defamed me!" "The article in the paper sullied my reputation"

maleficent - harmful or evil in intent or effect

malevolent, malicious - wishing or appearing to wish evil to others; arising from intense ill will or hatred; "a gossipy malevolent old woman"; "failure made him malevolent toward those who were successful"

harmful - causing or capable of causing harm; "too much sun is harmful to the skin"; "harmful effects of smoking"

unkind - lacking kindness; "a thoughtless and unkind remark"; "the unkindest cut of all"

maleficent - harmful or evil in intent or effect