get under one's skin, get - irritate; "Her childish behavior really get to me"; "His lying really gets me"

eat into, rankle, grate, fret - gnaw into; make resentful or angry; "The unjustice rankled her"; "his resentment festered"

chafe - feel extreme irritation or anger; "He was chafing at her suggestion that he stay at home while she went on a vacation"

peeve - cause to be annoyed, irritated, or resentful

ruffle - trouble or vex; "ruffle somebody's composure"

fret - cause annoyance in

beset, chevvy, chevy, chivvy, chivy, harass, harry, hassle, molest, plague, provoke - annoy continually or chronically; "He is known to harry his staff when he is overworked"; "This man harasses his female co-workers"

antagonize, antagonise - provoke the hostility of; "Don't antagonize your boss"

displease - give displeasure to

aggravate, exacerbate, worsen, exasperate - make worse; "This drug aggravates the pain"

chafe, gall, fret - become or make sore by or as if by rubbing

itch, rub, scratch - scrape or rub as if to relieve itching; "Don't scratch your insect bites!"

physiology - the branch of the biological sciences dealing with the functioning of organisms

stimulate, excite - act as a stimulant; "The book stimulated her imagination"; "This play stimulates"

vellicate, pinch - irritate as if by a nip, pinch, or tear; "smooth surfaces can vellicate the teeth"; "the pain is as if sharp points pinch your back"