alteration, change, modification - an event that occurs when something passes from one state or phase to another; "the change was intended to increase sales"; "this storm is certainly a change for the worse"; "the neighborhood had undergone few modifications since his last visit years ago"

detriment, hurt - a damage or loss

deformation, distortion - a change for the worse

ravel, ladder, run - a row of unravelled stitches; "she got a run in her stocking"

decay - an inferior state resulting from the process of decaying; "the corpse was in an advanced state of decay"; "the house had fallen into a serious state of decay and disrepair"

corrosion - a state of deterioration in metals caused by oxidation or chemical action

desolation, devastation - the state of being decayed or destroyed

decrepitude, dilapidation - a state of deterioration due to old age or long use

wear - impairment resulting from long use; "the tires showed uneven wear"

bowleg, genu varum, tibia vara - a leg bowed outward at the knee (or below the knee)

anorgasmia - absence of an orgasm in sexual relations

bad condition, poor shape, unfitness - poor physical condition; being out of shape or out of condition

disability of walking - a disability that interferes with or prevents walking

astasia - inability to stand due to muscular incoordination

amputation - a condition of disability resulting from the loss of one or more limbs

hearing disorder, hearing impairment - impairment of the sense of hearing

dysomia - impairment of the sense of smell

vision defect, visual defect, visual disorder, visual impairment - impairment of the sense of sight

descensus, prolapse, prolapsus - the slipping or falling out of place of an organ (as the uterus)

hypesthesia, hypoesthesia - impairment of tactile sensitivity; decrease of sensitivity

genu valgum, knock-knee, tibia valga - inward slant of the thigh

pigeon toes - disability in which the toes are turned inward; often associated with knock-knee

bandy legs, bow leg, bow legs - outward curvature of the legs

scathe, damage, harm, hurt - the act of damaging something or someone

degradation, debasement - changing to a lower state (a less respected state)