| Noun | 1. | hybridization - (genetics) the act of mixing different species or varieties of animals or plants and thus to produce hybridsmonohybrid cross - hybridization using a single trait with two alleles (as in Mendel's experiments with garden peas) test-cross, testcross - a cross between an organism whose genotype for a certain trait is unknown and an organism that is homozygous recessive for that trait so the unknown genotype can be determined from that of the offspring | |