| Noun | 1. | Holmes - a fictitious detective in stories by A. Conan Doyle | |
| 2. | Holmes - United States jurist noted for his liberal opinions (1841-1935) | |
| 3. | Holmes - United States writer of humorous essays (1809-1894)author, writer - writes (books or stories or articles or the like) professionally (for pay) | |
| 4. | Holmes - English geologist and supporter of the theory of continental drift (1890-1965) | |