alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"

lay up - disable or confine, as with an illness; "She was laid up with pneumonia for six weeks"

nobble - disable by drugging; "nobble the race horses"

pinion - cut the wings off (of birds)

restrain, hold, confine - to close within bounds, limit or hold back from movement; "This holds the local until the express passengers change trains"; "About a dozen animals were held inside the stockade"; "The illegal immigrants were held at a detention center"; "The terrorists held the journalists for ransom"