Prairie State - a Midwest state in north-central United StatesMiddle West, Midwest - the north central region of the United States (sometimes called the heartland or the breadbasket of America) Cairo - a town at the southern tip of Illinois at the confluence of the Ohio and Mississippi Rivers Champaign - a university town in east central Illinois adjoining Urbana Chicago, Windy City - largest city in Illinois; a bustling Great Lakes port that extends 26 miles along the southwestern shoreline of Lake Michigan Decatur - a city in central Illinois; Abraham Lincoln practiced law here East Saint Louis - a town in southwest Illinois on the Mississippi across from Saint Louis Moline - a town in northwest Illinois on the Mississippi River Peoria - a city in central Illinois on the Illinois River Rock Island - a town in northwest Illinois on the Mississippi River; site of a Union prison during the Civil War Urbana - a university town in east central Illinois adjoining Champaign Illinois River - a river in Illinois that flows southwest to the Mississippi River |