| Noun | 1. | Middle West - the north central region of the United States (sometimes called the heartland or the breadbasket of America)Missouri, Show Me State, MO - a midwestern state in central United States; a border state during the American Civil War, Missouri was admitted to the Confederacy without actually seceding from the Union Buckeye State, OH, Ohio - a midwestern state in north central United States in the Great Lakes region | |