| Noun | 1. | Lophophora williamsii - a small spineless globe-shaped cactus; source of mescal buttonscactus - any spiny succulent plant of the family Cactaceae native chiefly to arid regions of the New World genus Lophophora, Lophophora - two species of small cacti of northeastern Mexico and southwestern United States having rounded stems covered with jointed tubercles: mescal | |